Vacatures
>
Amsterdam

    A postdoc position in CAR NK cell development - Amsterdam, Nederland - Sanquin

    Sanquin
    Sanquin Amsterdam, Nederland

    1 week geleden

    Default job background
    Beschrijving
    A postdoc position in CAR NK cell development

    Sanquin Research is looking for a postdoctoral researcher for a project to work on NK cell therapy. The focus will be on understanding the general killing mechanisms in place and the process of enhancing NK cell cytotoxicity against tumor cells by instructive Chimeric Antigen Receptor introduction. This project is part of a program to develop a solid base to develop therapeutic options for additional cancer treatment of solid tumors. It consists of a collaboration between different groups within Sanquin, making optimal use of NK cell knowledge, culture experience and CAR technology that will be combined in a joint cellular immunotherapy program against cancer. The research group in which the position is available, has both experience and tools to study this process on CAR technology and NK cell biology. Apart from close collaboration on the mechanisms of culture, expansion and NK cell killing we also collaborate with colleagues at the Netherlands Cancer Institute to advance the right technological steps toward targeting susceptible tumors in ex-vivo tissue and future in-vivo approaches. About Sanquin

    The mission of Sanquin is: "Together with the donor we ensure a better life for patients". Sanquin is a knowledge-driven not-for-profit organization that supplies life-saving products and services, as well as blood transfusion medicine- and immunology- related research. The research is performed by a dedicated staff and it is focused around four medical priorities: 1. Anemia, 2. Bleeding and Hemostasis, 3. Cellular Immunotherapy, 4. Inflammation and Immunity. Sanquin's research portfolio is divided into strategic research (ranging from basic to applied and clinical research) and product- and process development.

    The Innate Immunity group

    You will be based at Sanquin, a renowned research institute that harbors several research groups that study hematology, immunology and cellular therapies, providing a solid and capable critical mass. Moreover, there is a close collaboration between the innate immunity and immunotherapy groups on NK cells within the research program.

    In addition, Sanquin provides a lively, internationally oriented, scientific environment with excellent facilities. We also organize weekly scientific meetings, journal clubs and work discussions to gain scientific input and to exchange knowledge. As a leading research institute in the field of cellular immunology Sanquin offers a postdoctoral position under good supervision in a scientifically oriented setting with unique expertise in cellular therapy development.

    What you will do

    As a full member of our Innate Immunity Group you will further develop current culture and test systems to determine the mechanisms of boosting cytotoxicity to improve NK cell-derived cytotoxicity against target cells.

    Our expertise on innate immunity and the many functional assays available will be combined with NK cell knowledge on culture and expansion. The functional findings of the work on generating potent CAR NK cells may bear immediate relevance to acute off-the shelf treatment in oncological patients as our ultimate goal together with our wide network of collaborators.

    We are looking for an enthusiastic postdoctoral researcher with good communication skills and an affinity with translational research

    · A PhD degree in biology, (bio)molecular/biomedical/pharmaceutical sciences or equivalent.
  • some experience in molecular biology will be a competitive advantage;
  • an independent, responsible and team-oriented candidate;
  • good communication and writing skills in English.
    • Our offer
  • a challenging translational project in a multi-disciplinary and enthusiastic (inter)national team;
  • temporary position (project duration of 3 years);
  • salary and conditions are conform CAO Sanquin;
  • 8.33% end-of-year bonus; i.e. a thirteenth month in case of full-year employment;
  • partial reimbursement of travel costs;
  • pension plan with Pensioenfonds Zorg & Welzijn (PFZW);
  • at fulltime employment (36 hours) 201 hours of leave per annum.
    • Learn more about our terms of employment at

    More info

    Information can be obtained from Robin van Bruggen, , and Taco Kuijpers, Does this vacancy trigger you, do you recognize yourself in this profile? Please send us your motivation letter (explaining why this specific position is interesting for you, how would your skillset fit this research), together with your curriculum vitae both in English. Please send your application accompanied by a cover letter (in English) before the 12th of May 2024. Please note that we will only process applications from candidates who have a valid work permit for the EU. A pre-employment screening will be part of the onboarding procedure.

    Acquisition is not appreciated. Sanquin does not accept unsolicited help from agencies for vacancies. CV's sent (in any form whatsoever) by placement agencies to any Sanquin employee without a valid written assignment by HR Sanquin will be considered property of Sanquin for which no compensation is owed in any way..
  • Neogene Therapeutics

    Bioinformatician

    2 dagen geleden

    Neogene Therapeutics Amsterdam, Nederland

    Pushing the frontier of solid cancer therapy, Neogene Therapeutics is a global, clinical stage biotechnology company built on the premise of innovation and novel paradigm-changing science. Using tumor mutation profiles to engineer fully individualized T cell therapies, Neogene is ...

  • Sanquin

    Phd Student B Cell Modulation By Antibodies

    1 dag geleden

    Sanquin Amsterdam, Nederland

    **Location** · - Amsterdam · **Working week** · - 36 hours · **Education** · - WO · **Closing date** · - 10 May 2024 · **Function area** · - Research / Laboratory · **Vacancy nr.** · - 1078 · **About Sanquin** · Sanquin Blood Supply Foundation combines medical, diagnostic, blood ...

  • SanaGen B.V.

    Research Technician

    4 dagen geleden

    SanaGen B.V. Amsterdam, Nederland

    **Bedrijfsomschrijving** · - SanaGen was incorporated in 2019 and is headquartered at the Health Innovation District in Amsterdam, The Netherlands. SanaGen focuses on gene therapy approaches for rare genetic disorders that can provide a life-long cure for many diseases. SanaGen i ...

  • Brainlab

    Sales Representative Medical Technology

    4 dagen geleden

    Brainlab Amsterdam, Nederland

    **Company Description** · Founded in Munich, Germany in 1989, Brainlab develops, manufactures and markets software-driven medical technology, enabling access to improved, more efficient, less-invasive patient treatments. Our key to success is our creative, talented and hard-worki ...

  • Kelly Services

    Interim Manager Communications Benelux

    3 dagen geleden

    Kelly Services Amsterdam, Nederland

    Published · 16-Apr-2024 · Salary · € €95.00 Hourly · Location · Amsterdam · Category · Temporary · Sector · Marketing · Reference · BBBH669779 · Work Model · Hybrid · Description · Our client is a management consulting firm and they are immediately looking for a an Interim Manage ...

  • United Airlines

    Supervisor, Airport Operations

    4 dagen geleden

    United Airlines Amsterdam, Nederland

    **Description**: · There's never been a more exciting time to join United Airlines. We're on a path toward becoming the best airline in the history of aviation. Our shared purpose - Connecting People, Uniting the World - is about more than getting people from one place to another ...

  • Universiteit van Amsterdam

    Phd Candidate in Rna Based Gene Regulation in

    1 week geleden

    Universiteit van Amsterdam Amsterdam, Nederland

    **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Master**Functie type**:Promotieplaats**Sluitingsdatum**: **Vacaturenummer**:12866- · - If the intricate dance of RNA molecules sparks your curiosity, we invite you to join our quest to decode ...

  • Adidas

    Business Performance Analyst

    3 dagen geleden

    Adidas Amsterdam, Nederland

    General Purpose: · - As the Manager of Analytics in the global Business Performance Analytics team, your role is multifaceted and pivotal in driving data-driven insights for our senior leadership team. You'll be at the forefront of automating reporting processes using Databricks, ...

  • Vrije Universiteit Amsterdam

    Phd Preventive Dentistry

    3 dagen geleden

    Vrije Universiteit Amsterdam Amsterdam Zuid, Nederland

    **Your function**: · **Project description** · Antibiotic resistance is a major and ever-increasing health threat, projecting to result in 10 million deaths annually by 2050. An often-overlooked cause for this resistance is the fact that many antibacterial agents are unable to ef ...

  • Amsterdam UMC

    Phd-student in Glial Drug Development

    1 week geleden

    Amsterdam UMC Amsterdam Zuid, Nederland

    **About the project**: · In recent years it has become increasingly clear that dysfunctional glia (astrocytes and microglia) play a major role in the pathogenesis of Alzheimer's disease. In specific, lipid droplets haven been shown to accumulate in the Alzheimer's disease brain, ...

  • Vrije Universiteit Amsterdam

    Postdoc Preventive Dentistry

    3 dagen geleden

    Vrije Universiteit Amsterdam Amsterdam Zuid, Nederland

    **Your function**: · **Project description** · Antibiotic resistance is a major and ever-increasing health threat, projecting to result in 10 million deaths annually by 2050. An often-overlooked cause for this resistance is the fact that many antibacterial agents are unable to ef ...

  • AMOLF

    Phd in Biophysics: Chaperone-guided Formation of

    1 week geleden

    AMOLF Amsterdam Oost, Nederland

    **PhD in Biophysics: Chaperone-guided formation of single protein complexes**: · **Work Activities**: · Do you want to discover how multi-protein assemblies are produced without error? The aim of this project is to reveal this vital cellular process at the single-molecule level. ...

  • AMOLF

    Postdoc: Chaperone-guided Formation of Single

    4 dagen geleden

    AMOLF Amsterdam Oost, Nederland

    **Work Activities**: · Do you want to discover how multi-protein assemblies are produced without error? The aim of this project is to reveal this vital cellular process at the single-molecule level. Our research group has been at the vanguard of studying chaperone-protein interac ...

  • AMOLF

    Postdoc: Chaperone-guided Formation of Single

    1 week geleden

    AMOLF Amsterdam Oost, Nederland

    **Postdoc: Chaperone-guided formation of single protein complexes**: · **Work Activities**: · Do you want to discover how multi-protein assemblies are produced without error? The aim of this project is to reveal this vital cellular process at the single-molecule level. Our resear ...

  • Marken

    Cell & Gene Control Tower Logistics Coordinator

    1 week geleden

    Marken Lijnden, Nederland

    **Job Title**: · Logistic Coordinator - Cell and Gene. · **Main Purpose**: · The Logistics Coordinator - Cell & Gene is responsible for providing an enhanced level of customer service and operational support for movement of any cell and gene shipment through our network. These ac ...

  • Marken

    Warehouse Associate

    5 dagen geleden

    Marken Lijnden, Nederland

    **Title**: · Warehouse Associate · **Job Purpose**: · The Warehouse Associate is responsible for stock management and overall warehousing for the Marken Branch. Will work in conjunction with all Marken operated branches and their agents. · **Main Duties and Responsibilities**: · ...

  • Toxys

    We Are Looking for a Lab Technician for Our Genetic

    1 dag geleden

    Toxys Oegstgeest, Nederland

    **About Toxys** · Toxys is a Dutch biotech company that develops innovative in vitro solutions for safety testing of novel pharmaceutical compounds, chemicals, cosmetics, and food ingredients. Toxys developed ToxTracker, a unique stem cell-based reporter assay for early identific ...

  • Genmab

    Intern, Translational Data Science

    1 week geleden

    Genmab Utrecht, Nederland

    At Genmab, we're committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, ca ...

  • UMC Utrecht

    Phd Position in Biofabrication and Bioprinting for

    1 week geleden

    UMC Utrecht Utrecht, Nederland

    We are seeking an ambitious PhD student for our multidisciplinary team to build new technological solutions for developmental biology and preclinical research. You will develop bioprinted tissues to generate and expand hematopoietic stem cells.**Elke dag de zorg en de gezondheid ...

  • Prinses Máxima Centrum

    Internship Cell and Gene Therapy Facility

    1 week geleden

    Prinses Máxima Centrum Utrecht, Nederland StageSHIP

    General Info Cure every child with cancer, with optimal quality of life. That is the mission of the Princess Máxima Center. The Princess Máxima Center is located in Utrecht as a national center for all children and adolescents with cancer. Every year, about 600 children in the Ne ...