Research Associate, Biochemical Analysis - Utrecht, Nederland - Genmab

Beschrijving

At Genmab, we're committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

Genmab is focused on creating and developing innovative and differentiated antibody products to improve the lives of cancer patients.

Role

You will be part of the Biochemical Analysis department, where four teams are closely connected and focused on manufacturing and characterizing lead candidates.

This vacancy is part of the CMC-Developability team, which is specifically responsible for providing developability and stability assessments for selected lead panels to predict potential risks during the drug development of the final lead candidate. Our expertise supports other teams in developing processes to mitigate these risks. Within our team, we constantly seek to improve existing techniques and introduce new analytical methods.

Responsibilities

· You perform experiments determining the melting point (Tm) and Onset of aggregation (Tagg) using the UNcle system and determine solubility (PEG assay).

· You perform experiments using a wide range of modern biochemical techniques in several simultaneous projects (e.g., CE-SDS, HPLC/UPLC, icIEF, etc.)

· You work closely with scientists and other research associates in multiple project teams, supporting each other constantly as a team

· You document and report the results in a clear and timely manner.

· Most of the work is performed according to Job Instructions (JI's) and therefore requires high accuracy.

· You communicate with different stakeholders about requests and updates

· You contribute to the optimization and innovation of our team.

· You act as a Subject Matter Expert (SME) of one or more instruments

Requirements

You are keen and motivated to use your up-to-date knowledge in protein biochemistry and experience with biochemical techniques to strengthen our team. You are precise and accurate in the execution of experiments and the documentation of the results. You have good communication skills, a service-oriented attitude and can deal with changing priorities and unexpected workloads. You like to work in a team, but you can also work independently.

In addition, you meet the following professional requirements:

· You have a HLO (Bachelor's) degree or equivalent in Biochemistry, Chemistry, Life Science or other relevant fields

· 0-2 years of experience in the Biochemistry area

· Experience and/or a good understanding of protein analysis, preferably antibodies, is advantageous.

· You have knowledge and experience with commonly used biochemical analysis techniques such as Absorbance Spectroscopy, Capillary Electrophoresis (CE-SDS, icIEF), Analytical Chromatography (HPLC)

· Experience with Dynamic Light Scattering (DLS) and Differential Scanning Fluorimetry (DSF) is an advantage

· You can work successfully on several projects in parallel in a fast-paced environment and with tight timelines

· You are motivated by delivering high-quality output and are used to working according to a quality system

· An interest in software and data handling is an advantage.

· You have good relational and communication skills in English, as this is Genmab's business language

Genmab employees work with determination and with respect for each other, consistent with our core values, to achieve our common goals. We give individuals and teams the autonomy to drive the development of innovative products and solutions, knowing that integrity is a core value throughout our company. Genmab will offer the successful application a challenging position. The right candidate will have the opportunity to work with highly specialized people across functions in an informal, multicultural culture, all aiming to make a difference for cancer patients.

About You

• You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
• You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with diverse backgrounds
• You are determined to do and be your best and take pride in enabling the best work of others on the team
• You are not afraid to grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you're in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.