- Representation: act as a deputy of the team manager when neededand support the processdevelopment management.
- Leadership: provide strong scientific, technical and regulatoryleadership at project level. Lead individual scientists and labtechnicians on complex projects.
- Projects: lead multi-disciplinary matrix teams on complex projects inthe area of scientific expertise. Lead problem solving and lessonslearned activities.
- Scientific tasks: design of advanced experimental plans and their execution, in process data analysis, write and review high quality reports.
- Customer interactions: develop strong customer relationships.
- Training: lead training activities in the area of expertise.
- Provide solutions to identified risks, issues, problems. Report issues ina timely fashion.
- Facilitate improvements to departmental business processes andcontribute to the implementation of innovative technologies.
- Demonstrate flexibility to support other activities within the department.
- Proactive approach to own continuous professional development.
- Deep Understanding of IVT criticalprocessparameters, reactionoptimization and scale-up.
- Experience in mRNA manufacturing in batch and controlled (bioreactor) modalities.
- Experience with a widerangeof mRNA analyticaltechniquesfor large nucleicacidmolecules, in particularwithanalyticalassaysassociatedwith IVT and purificationprocesses.
- Implementation of DOE studies & high-throughputscreeningfor IVT and purificationprocesses.
- Knowledge oftechnologytransfer and GMP manufacturing.
- General understanding and experienceofpurificationtechniques such aschromatography (includingaffinity, ionexchangehydrophobicinteractions, etc.) and tangential flowfiltration (TFF).
- Demonstratedabilitytoefficientlywork in a fast paced and fluid environment.
- Knowledge ofmolecularbiology and mRNA constructs design.
- Experience withinthemanufacturingof large mRNA moleculesincludingself-amplifying RNAs and circularRNAswould be a plus.
- General understandingofthe mRNA-LNP encapsulationprocess and relevant associatedanalyticalmethods.
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Scientist LNP Innovation
Gevonden in: Jooble NL O C2 - 17 uur geleden
Lonza Group Ltd. Geleen, Nederland(Principal/Senior) Scientist LNP Innovation page is loaded · (Principal/Senior) Scientist LNP Innovation · Apply locations NL - Geleen time type Full time posted on Posted Today job requisition id R59457 Today, Lonza is a global leader in life sciences operating across three c ...
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Scientist LNP Innovation
Gevonden in: Talent NL C2 - 1 dag geleden
Lonza Geleen, NederlandToday, Lonza is a global leader in life sciences operating across three continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exc ...
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Scientist Oxford Nanopore Sequencing
Gevonden in: Talent NL C2 - 4 dagen geleden
Lonza Geleen, NederlandToday, Lonza is a global leader in life sciences operating across three continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exc ...
Principal Scientist mRNA - Geleen, Nederland - Lonza
Beschrijving
Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world, and that's the kind of work we want to be part of.
For mRNA Business unit, located in Geleen, Netherlandswe have exciting opportunities. Become part of a group that enables its customers to meet some of the greatest challenges in patient treatment and join us by applying for the position as a PrincipalScientistmRNA in Process Development.
Key responsibilities:
Key requirements:
Every day, Lonza's products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.
People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfactionthatcomeswithmaking a meaningfuldifference.
Reference: R58617